Breast cancer is the most common cancer in women, and is inherently heterogeneous at both the morphological and molecular levels.1 The evolutionarily conserved forkhead box (FOX) transcription factor family plays an essential role in various biological processes. Although the involvement of several FOX genes in breast cancer has been reported,2 limited work has been performed on the FOX gene family profiling in different subtypes of breast cancer, especially regarding the cell type-specific variation of the FOX gene family members.